Chondrosarcoma
Malignant cartilage-forming tumour, typically affecting adults over 40.
Chondrosarcoma is a malignant tumour that produces cartilage matrix and is most commonly located in the pelvis, femur, and proximal humerus. Unlike other bone sarcomas, it usually arises de novo rather than from a pre-existing lesion.
It has several subtypes, including conventional, clear cell, mesenchymal, and dedifferentiated variants.
Radiographically, it shows cortical destruction and rings-and-arcs calcification. Biopsy confirms diagnosis.
This tumour is generally resistant to chemotherapy and radiotherapy; therefore, wide surgical resection remains the mainstay of treatment.
Prognosis varies based on grade and subtype, with dedifferentiated types carrying a poorer outcome.
