Serkan BAYRAM

Endoprosthesis

reconstruction is a cornerstone technique in musculoskeletal oncology, allowing immediate restoration of skeletal continuity and early mobilization after wide tumor resection. Modern modular megaprostheses, made of titanium or cobalt-chromium alloys, are designed for durability, functional recovery, and ease of revision. They are primarily indicated for periarticular or diaphyseal bone loss following tumor excision, failed fixation, or pathological fractures. Cemented fixation ensures immediate stability, while press-fit and porous-coated designs promote biological integration. Despite excellent limb salvage rates (>90%), complications such as infection, aseptic loosening, and mechanical failure remain challenges. Advances including silver-coated implants, expandable pediatric prostheses, and improved soft-tissue reattachment techniques continue to enhance long-term outcomes and quality of life for oncology patients.