Tarsal Tunnel Syndrome (TTS)

M.D. Alparslan Uzun· Istanbul Medipol University, School of Medicine, Department of Orthopedics and Traumatology
Apr 25, 2026

Definition

·      The most common compression neuropathy affecting the foot and ankle

·      Leads to pain and paresthesia of the plantar foot

Anatomy

·      The flexor retinaculum bridges the leg fascia proximally and the fascia of abductor pollicis distally

·      Posterior tarsal tunnel

o   Flexor retinaculum, calcaneus (medial), talus (medial), abductor hallucis (inferior)

o   Contents: tibial nerve, posterior tibial artery, FHL, FDL, tibialis posterior

·      Anterior tarsal tunnel

o   Flattened surface defined by inferior extensor retinaculum and fascia overlying talus and navicula

o   Contents: deep peroneal nerve, peroneus tertius, EHL, EDL, dorsalis pedis a.

·      The posterior tibial nerve has 3 terminal branches

o   Medial plantar

o   Lateral plantar

o   Medial calcaneal

·      These 3 nerves most commonly branch within the tarsal tunnel

·      Medial & lateral plantar nerves travel in their own fibrous tunnel distal to tarsal tunnel

·      Distal TTS: compression of the first branch of the lateral plantar nerve

 

Etiology

·      Intrinsic

o   Masses (ganglion cysts, lipoma, neurilemmoma, varicous vein)

o   Tenosynovitis of the tendons in tarsal tunnel

o   Perineural fibrosis & osteophytes

 

·      Extrinsic

o   Biomechanical malalignment of the foot and ankle

o   Soft tissue and osseous trauma

o   Iatrogenic injury to lateral plantar nerve

§  Can occur during procedures on the plantar surface of the hindfoot

§  Particularly at risk during retrograde insertion of arthrodesis nail

Evaluation

·      Pain is characterized as burning and paresthesias

·      May present as a part of the “heel pain triad”

o   Posterior tibial tendon deficiency, plantar fasciitis, tarsal tunnel syndrome

o   due to loss of static and dynamic stabilizers of the medial arch and susequent traction neuropathy

·      Aggrevated by walking, prolonged standing, running

·      Usually radiates distally and proximally

·      Positive Tinnel sign along the distribution of the tibial nerve

·      Motor and sensory examinations are usually normal

·      Pressure within the tarsal tunnel increases with ankle dorsiflexion and foot eversion – may be used as a diagnostic tool to reproduce symptoms

·      Electrodiagnostic studies are accurate in 80-90% of patients

o   Sensory nerve conduction tests are more likely to be abnormal than motor nerve conduction velocity tests

o   More useful in diagnosing proximal causes of nerve entrapment

o   Needle electromyography is questionable

Imaging

·      Weight bearing radiographs to see any anatomical disruption

·      MRI is useful to detect space occupying masses and synovitis

·      CT may help in cases of osseous impingement

Treatment

·      Non-surgical

o   NSAIDs, local corticosteroid injections and immobilization are used to reduce inflammation in the tarsal tunnel                     

o   Immobilization in a removable boot or cast is recommended after steroid injections to prevent iatrogenic tibialis posterior tendon rüptüre

o   Custom orthoses may be beneficial if malalignment is present

·      Surgical

o   After 3-6 months of failed conservative management

o   Procedure

§  Successful outcomes in 50-90% of patients

§  The tibial nerve should be identified proximal to the tarsal tunnel and decompressed including release of flexor retinaculum

§  Medial and lateral plantar nerves and medial calcaneal nerve should be decompressed

§  Distal tarsal tunnel release is indicated if the patient has chronic plantar medial heel pain

§  The first branch of the lateral plantar n. (Baxter n.) should be decompressed by releasing the deep fascia of abductor hallucis

§  Wrapping the nerve with autologous veins may prevent scarring

 

o   The best results are seen in patients with:

§   Symptoms in distribution of the tibial nerve

§  Positive tinnel sign

§  Positive electrodiagnostic studies

§  Space occupying masses

o   Suboptimal results

§  Double crush syndrome

§  Inadequate release

§  Postoperative hematome formation

§  Scarring around the nerve

§  Improper diagnosis