Negative Pressure Wound Therapy (NPWT)

A wound management technique applying controlled negative pressure via a sealed dressing system Promotes wound healing by: Removing exudate Reducing oedema Improving local perfusion Commonly used as a temporary bridge in orthoplastic management

Prof. Dr. Adnan KARA · Istanbul Medipol University, Department of Orthopaedics and Trauma
Apr 29, 2026

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Mechanism of Action

  • Continuous or intermittent sub-atmospheric pressure

  • Leads to:

    • ↓ Interstitial oedema

    • ↑ Blood flow

    • Mechanical stimulation of tissue (“microdeformation”)

    • ↓ Bacterial load

Indications

  • Open fractures

  • Soft tissue defects

  • Post-debridement wounds

  • Temporary coverage before flap or graft

  • Chronic wounds (selected cases)

Orthoplastic Role

  • Used between debridement and definitive coverage

  • Helps:

    • Maintain wound environment

    • Prepare wound bed

    • Control exudate

Bridge therapy—not definitive treatment

Application Technique

  • Foam dressing placed in wound

  • Covered with occlusive film

  • Connected to suction device

Typical Settings

  • −75 to −125 mmHg

  • Continuous or intermittent

Benefits

  • Reduces wound oedema

  • Promotes granulation tissue

  • Protects exposed structures temporarily

  • Improves wound bed quality

Limitations

  • Does NOT replace:

    • Adequate debridement

    • Early flap coverage

  • Overuse may delay definitive treatment

Contraindications

  • Untreated necrotic tissue

  • Active infection without debridement

  • Malignancy in wound (relative)

  • Exposed vital structures without protection

Complications

  • Delayed definitive coverage

  • Bleeding

  • Pain during dressing changes

  • Foam retention (rare)

Timing Considerations

  • Should be used short-term only

Ideal:

  • As a bridge to coverage (<5–7 days)

Prolonged use → increased infection risk

Comparison with Standard Dressings

  • NPWT:

    • Better exudate control

    • Improved wound bed preparation

  • but; No proven superiority over early flap coverage

Pits & Pearls

  • NPWT is a bridge, not a destination

  • Always combine with proper debridement

  • Plan definitive coverage before applying NPWT

  • Useful in staged orthoplastic protocols

Pitfalls

  • Using NPWT as a long-term solution

  • Applying over necrotic tissue

  • Delaying flap unnecessarily

  • Ignoring need for repeat debridement