Growth Modulation & Guided Growth

Growth modulation refers to controlled alteration of physeal growth to gradually correct deformity in skeletally immature patients. Guided growth is the most common clinical application, using temporary hemiepiphysiodesis to harness remaining growth for angular correction.

Assoc. Prof. Mehmet Selcuk SAYGILI · Cemil Tascioglu City Training and Research Hospital, Istanbul
Apr 29, 2026

Core Principle

The physis can be selectively restrained on one side
→ continued growth on the opposite side leads to gradual correction

This concept is based on the Hueter–Volkmann principle:

  • Increased compression → decreased growth

  • Reduced compression → increased growth

Indications

Coronal plane deformities

  • Genu varum

  • Genu valgum

Sagittal plane deformities

  • Flexion deformity

  • Recurvatum (selected cases)

Specific conditions

  • Idiopathic deformities

  • Blount disease (early stages)

  • Rickets / metabolic bone disease

  • Skeletal dysplasia (selected patients)

Contraindications

  • Skeletal maturity

  • Physeal closure or damage

  • Severe deformity requiring immediate correction

  • Poor remaining growth potential

Techniques

Temporary Hemiepiphysiodesis (Guided Growth)

  • Most commonly used method

  • Uses implants to tether one side of physis

Implants:

  • Tension band plate (8-plate)

  • Staples (historical, less used)

  • Transphyseal screws (selected cases)

Permanent Epiphysiodesis

  • Used for limb length discrepancy

  • Not reversible

  • Not considered guided growth

Mechanism of Correction

  • Gradual angular correction over time

  • Correction rate depends on:

    • Age

    • Physeal activity

    • Deformity location

Typical correction rate:

  • Distal femur: ~0.7–1° per month

  • Proximal tibia: ~0.5–0.7° per month

Preoperative Planning

  • Full-length standing radiographs

  • Mechanical axis analysis

  • Determine:

    • Deformity origin

    • Remaining growth

Surgical Technique (Guided Growth)

  • Minimally invasive

  • Plate placed extraperiosteally

  • Screws inserted across metaphysis and epiphysis

Goal:

  • Tether growth without damaging physis

Postoperative Management

  • Immediate weight-bearing allowed

  • Routine follow-up every 3–4 months

  • Radiographic monitoring

Timing

  • Requires accurate prediction of remaining growth

  • Overcorrection risk if implants not removed in time

Complications

  • Overcorrection

  • Undercorrection

  • Implant failure

  • Screw breakage

  • Physeal damage (rare)

  • Rebound deformity after removal

Prognosis

  • Excellent in idiopathic deformities

  • Variable in pathological physes

  • Early intervention improves outcomes

Pits & Pearls

  • Timing is more important than technique

  • Distal femur corrects faster than proximal tibia

  • Always monitor regularly to avoid overcorrection

  • Rebound growth is common in younger patients

Pitfalls

  • Late intervention

  • Inadequate follow-up

  • Misidentifying deformity origin

  • Ignoring remaining growth potential

References

Stevens PM. Guided growth for angular correction: a preliminary series using a tension band plate. J Pediatr Orthop. 2007.

Stevens PM, Klatt JB. Guided growth for pathological physes: radiographic improvement during realignment. J Pediatr Orthop. 2008.

Burghardt RD, Herzenberg JE. Temporary hemiepiphysiodesis with the eight-plate. J Pediatr Orthop. 2010.

Boero S, Michelis MB. Guided growth for correction of knee deformities in children. J Child Orthop. 2011.

Danino B, Rödl R. Growth modulation techniques in paediatric orthopaedics. EFORT Open Rev. 2018.