Core Concept
HTO realigns the mechanical axis to unload the medial compartment
Primary goal: shift the weight-bearing axis to neutral or slight valgus — Fujisawa point: 62–66% of tibial plateau width
Bridge treatment: buys 10–15 years before TKA in well-selected patients
Indications
Symptomatic medial compartment OA with varus malalignment (HKA <177°)
Age <65, high activity demand
Failed conservative management >3 months
Kellgren-Lawrence grade 2–3 (grade ≥3 acceptable in carefully selected cases — see survival data below)
Intact or reconstructable lateral and patellofemoral compartments
Bonus indications:
ACL-deficient knee + varus + medial OA → HTO reduces anterior tibial translation
Medial meniscus root tear + varus → combined HTO + root repair improves objective outcomes
Osteochondral lesion + varus malalignment → unloading prior to cartilage restoration
Contraindications
Lateral or patellofemoral compartment involvement
Inflammatory arthropathy
Fixed flexion contracture >15°
Severe osteoporosis
BMI >35 (relative)
Active smoker (relative — delayed union risk)
MOW vs LCW — Quick Comparison
Medial Opening Wedge | Lateral Closing Wedge | |
|---|---|---|
5-yr survival | 95.1% | 93.9% |
10-yr survival | 91.6% | 85.4% |
Posterior tibial slope | ↑ Increases | ↓ Decreases |
Patellar height | ↓ Decreases | ↑ Increases |
ROM (flexion) | Slightly better | — |
Fibula osteotomy | Not needed | Required |
Best for | ACL laxity (↑ slope helps) | Post-ACL reconstruction (↓ slope preferred) |
Bottom line: Comparable clinical scores for pain, Lysholm, and HSS. At 10 years, MOW shows significantly better survivorship. Choose based on slope management and associated pathology.
Survival Data
Timepoint | Survival |
|---|---|
5-year | ~93.9–95.1% |
10-year | 85.4–91.6% |
10-year (KL ≥3) | 74.6% (still viable in selected patients) |
>10-year TKA conversion | ~11.2% |
Annual failure rates markedly increase after 10 years — counsel patients accordingly.
Risk Factors for Failure
OA Grade: KL >2 is a significant independent predictor of failure. Grade ≥3 requires careful patient selection.
Age paradox: Younger patients fail sooner.
Age 40–49 → TKA conversion rate 14.2%
Age 50–59 → 6.7%
Age 60–69 → 2.3%
Joint Line Obliquity (JLO): Target neutral JLO (177°–183°) postoperatively. Deviation → worse WOMAC, stiffness, and function. MPTA should remain ≤95°.
Concomitant cartilage repair (microfracture, ACI): Does not significantly improve overall survivorship vs isolated HTO. Select wisely.
Surgical Pearls
Don't overcorrect. Target 2–3° valgus of mechanical axis. Overcorrection → lateral compartment overload and technically demanding TKA later.
Hinge fracture = most feared intraoperative complication. Preserve a 10–15 mm lateral hinge.
Slope matters. MOW increases posterior tibial slope — advantage in ACL-deficient knees, disadvantage after ACL reconstruction.
Conversion to TKA — What to Expect
Prior HTO makes TKA technically more challenging: altered anatomy, soft tissue scarring, bone loss, residual deformity
TKA revision rate after HTO: OR 2.09 vs primary TKA
Most common failure modes: aseptic loosening, deep infection
Stemmed tibial implants often required for stability
Neutral JLO at index HTO → significantly better TKA outcomes later
Ideal Patient Profile
Age <65 · Varus malalignment · KL 2–3 · Intact lateral compartment · High activity demand · BMI <35
Pitfalls
1. Inadequate Deformity Analysis
Focusing only on the tibia and missing a femoral component
Performing a single osteotomy in multiapical deformities → residual malalignment
Lack of full-length standing alignment radiographs → most common planning error
2. Overcorrection / Undercorrection
Overcorrection (>3–5° valgus)
→ lateral compartment overload
→ accelerated lateral OA
→ technically more difficult future TKAUndercorrection
→ persistent symptoms
→ early failure
Most common cause of failure: incorrect target alignment
3. Ignoring Posterior Tibial Slope
MOW → increases slope
LCW → decreases slope
Common mistakes:
Performing MOW after ACL reconstruction → increased graft stress
Failing to adjust slope in ACL-deficient knees → persistent instability
4. Lateral Hinge Fracture
Most critical intraoperative complication
Risk factors:
Thin hinge (<10 mm)
Excessive opening
Incorrect osteotomy orientation
Consequences:
Loss of correction
Nonunion
Reoperation
5. Joint Line Obliquity (JLO) Malalignment
JLO outside 177°–183° range
→ altered knee biomechanics
Results:
Poor functional outcomes
Increased joint loading
More challenging future TKA
6. Neglecting the Patellofemoral Joint
Unrecognized PF degeneration → persistent anterior knee pain
MOW may lead to patella baja, worsening PF symptoms
7. Incorrect Indications
Tricompartmental OA → poor outcomes
Advanced OA (KL ≥4) → limited benefit
Inflammatory arthritis → continued disease progression
8. Underestimating Biological Factors
Smoking → delayed union / nonunion
Osteoporosis → compromised fixation stability
9. Technical Errors
Inadequate fixation → loss of correction
Large opening wedge without graft → nonunion
Skipping fibular osteotomy in LCW → technical complications
10. Poor Future TKA Planning
Excessive correction
Residual abnormal JLO
Leads to:
Technically demanding TKA
Need for stemmed implants
Higher complication rates
References:
Loke, R. W. K., et al. (2025). "Conversion to Total Knee Arthroplasty After High Tibial Osteotomy: A Systematic Review and Meta-analysis." The Orthopaedic Journal of Sports Medicine.
Herman, B. V., & Giffin, J. R. (2016). "High tibial osteotomy in the ACL-deficient knee with medial compartment osteoarthritis." Journal of Orthopaedics and Traumatology.
Chen, X., et al. (2020). "Higher risk of revision in total knee arthroplasty after high tibial osteotomy: a systematic review and updated meta-analysis." BMC Musculoskeletal Disorders.
Efe, T., et al. (2011). "Closing-wedge high tibial osteotomy: survival and risk factor analysis at long-term follow up." BMC Musculoskeletal Disorders.
Dal Fabbro, G., et al. (2024). "High survivorship rate and good clinical outcomes after high tibial osteotomy in patients with radiological advanced medial knee osteoarthritis: a systematic review." Archives of Orthopaedic and Trauma Surgery.
Kim, J.-H., Kim, H.-J., & Lee, D.-H. (2017). "Survival of opening versus closing wedge high tibial osteotomy: A meta-analysis." Scientific Reports.
Maniar, A. R., et al. (2026). "Improved clinical outcomes when maintaining a neutral joint line obliquity at high tibial osteotomy and subsequent total knee arthroplasty." Journal of Experimental Orthopaedics.